TRBVA

Across TCGA pan-cancer cohorts, TRBVA RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated TRBVA data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher TRBVA RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRBVA expression acts as an unfavorable survival marker.

BLCA, UCEC, and KIRP are the cancer types where TRBVA RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	III,IV	0.124	0.551	<.001	81	view →
UCEC	DFS	Tertile	All	0.633	0.852	<.001	54	view →
KIRP	OS	Tertile	II,III,IV	0.180	0.771	.007	36	view →
KIRC	OS	Tertile	II,III,IV	0.301	0.539	.018	24	view →
GBM	OS	Tertile	All	0.153	0.418	.022	18	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
PRAD	OS	Tertile	All	0.939	0.995	.006	12	view →
SARC	OS	Tertile	All	0.511	0.861	<.001	12	view →
LIHC	DFS	Tertile	II,III,IV	0.100	0.463	.048	9	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

TRBVA–BLCA (DFS)

Open the BLCA breakdown →