Q-omics provides the consensus-scored TRBVA profile across patient tissues and cancer cell-line models. TRBVA expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in BLCA. Additionally, TRBVA RNA expression shows 10,241 significant gene co-expression associations, with the highest sampling consensus in BRCA. Together, these results highlight BLCA, and BRCA as cancer lineages where TRBVA shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Premium analyses for TRBVA — synthetic lethality, tumor antigen, and pembrolizumab response.

View premium →

Survival associations

This table summarizes TRBVA survival associations across molecular data types. TRBVA RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

TRBVA data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	9	BLCA (81)	view →

This table ranks reproducible TRBVA RNA expression–survival associations across cancer types. High TRBVA expression shows unfavorable associations in BLCA, UCEC, KIRP, KIRC, SKCM and GBM. The BLCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BLCA as the clearest survival context for TRBVA RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	III,IV	0.124	0.551	<.001	81	view →
UCEC	DFS	Tertile	All	0.633	0.852	<.001	54	view →
KIRP	OS	Tertile	II,III,IV	0.180	0.771	.007	36	view →
KIRC	OS	Tertile	II,III,IV	0.301	0.539	.018	24	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
GBM	OS	Tertile	All	0.153	0.418	.022	18	view →

Pink = unfavorable, green = favorable. all 9 lineages →

TRBVA-BLCA (DFS)

Kaplan–Meier survival curve for TRBVA RNA expression in BLCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with TRBVA in patient tissues and cancer cell lines. In patient samples, TRBVA shows the broadest associations at the RNA and protein expression levels, with BRCA recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	10,241	BRCA (4008)	view →
Protein (mass-spec)	10,125	LSCC (3921)	view →