TRBV29-1

Across TCGA pan-cancer cohorts, TRBV29-1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of TRBV29-1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TRBV29-1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRBV29-1 is over-expressed in tumor, although a few such as COAD and LUSC show the opposite, repressed pattern.

KIRC, COAD, and LUSC are the cancer types where TRBV29-1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRBV29-1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+1.847	<.001	10	view →
COAD	All	II,III,IV	−0.819	<.001	10	view →
LUSC	Male	All	−0.855	<.001	6	view →
THCA	All	All	−0.837	<.001	6	view →
UCEC	All	All	−0.543	.023	2	view →
STAD	Female	III,IV	+2.600	.005	1	view →
KIRP	All	All	+0.508	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

TRBV29-1–KIRC

Open the KIRC breakdown →