TRBV25OR9-2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, TRBV25OR9-2 RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated TRBV25OR9-2 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher TRBV25OR9-2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRBV25OR9-2 expression acts as an unfavorable survival marker.

BLCA, BRCA, and LIHC are the cancer types where TRBV25OR9-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCADFSTertileAll0.2420.629.00372view →
BRCADFSTertileII,III,IV0.8060.943.00254view →
LIHCDFSTertileAll0.1060.553.0479view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TRBV25OR9-2–BLCA (DFS)

Kaplan–Meier survival curve for TRBV25OR9-2 RNA-high vs -low samples in BLCA.

Open the BLCA breakdown →

Exploration