TRBV25OR9-2

Across TCGA pan-cancer cohorts, TRBV25OR9-2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of TRBV25OR9-2’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where TRBV25OR9-2 RNA is repressed in tumor relative to normal tissue. In most cancer types TRBV25OR9-2 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

BRCA are the cancer types where TRBV25OR9-2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRBV25OR9-2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	II,III,IV	−0.048	.004	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

TRBV25OR9-2–BRCA

Open the BRCA breakdown →