TRBV23OR9-2

Across TCGA pan-cancer cohorts, TRBV23OR9-2 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated TRBV23OR9-2 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher TRBV23OR9-2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRBV23OR9-2 expression acts as an unfavorable survival marker, although some lineages such as UCS show a favorable association.

MESO, KIRP, and OV are the cancer types where TRBV23OR9-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Tertile	II,III,IV	0.156	0.400	<.001	162	view →
KIRP	OS	Tertile	All	0.208	0.713	<.001	51	view →
OV	OS	Tertile	IV	0.022	0.760	<.001	36	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
LIHC	OS	Tertile	II,III,IV	0.312	0.777	.004	36	view →
PCPG	OS	Tertile	All	0.032	0.948	<.001	27	view →
UCS	DFS	Quartile	II,III,IV	0.626	0.257	.021	18	view →
UCEC	DFS	Tertile	IV	0.206	0.704	.033	18	view →
THCA	DFS	Tertile	II,III,IV	0.100	0.763	.022	18	view →
PAAD	OS	Tertile	II,III,IV	0.422	0.625	.028	12	view →
THYM	DFS	Tertile	II,III,IV	0.083	0.881	<.001	9	view →
LGG	OS	Tertile	All	0.216	0.484	.009	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

TRBV23OR9-2–MESO (DFS)

Open the MESO breakdown →