TRBV22-1

Across TCGA patient cohorts, TRBV22-1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,256 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRBV22-1-associated proteins across cancer lineages are SEMA4A, RUNX3, and S100B. Each is linked with TRBV22-1 in more than 4 cancer types. Because this analysis shows association rather than direction, both TRBV22-1-to-partner and partner-to-TRBV22-1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRBV22-1 versus SEMA4A in UCEC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV22-1→partner) and Y-score (partner→TRBV22-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SEMA4A →	+0.658	+1.167	<.001	.005	3	5
CCRCC	RUNX3 →	+0.423	+0.336	<.001	.001	3	4
HNSC	S100B →	+0.853	+0.479	<.001	<.001	3	4
LSCC	SCLY →	+0.394	+0.472	<.001	<.001	3	4
LSCC	SEPTIN1 →	+0.603	+0.506	<.001	<.001	3	4
HNSC	SEPTIN1_S315 →	+0.921	+0.595	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,256 associations by consensus.

TRBV22-1 vs SEMA4A — UCEC

Explore this scatter interactively →