TRBV22-1

Q-omics provides the consensus-scored TRBV22-1 profile across patient tissues and cancer cell-line models. TRBV22-1 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in STAD. Additionally, TRBV22-1 RNA expression shows 13,256 significant protein co-abundance associations, with the highest sampling consensus in PDAC. Together, these results highlight STAD, and PDAC as cancer lineages where TRBV22-1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes TRBV22-1 survival associations across molecular data types. TRBV22-1 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

TRBV22-1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	14	STAD (108)	view →

This table ranks reproducible TRBV22-1 RNA expression–survival associations across cancer types. High TRBV22-1 expression shows unfavorable associations in STAD, MESO, LIHC, UCEC and KIRC, but favorable associations in LAML. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify STAD as the clearest survival context for TRBV22-1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	IV	0.068	0.480	<.001	108	view →
MESO	OS	Tertile	III,IV	0.077	0.580	<.001	90	view →
LIHC	DFS	Tertile	All	0.045	0.553	<.001	45	view →
UCEC	DFS	Tertile	All	0.603	0.845	<.001	36	view →
LAML	DFS	Median	All	0.646	0.482	.015	34	view →
KIRC	DFS	Tertile	All	0.229	0.634	.011	30	view →

Pink = unfavorable, green = favorable. all 14 lineages →

TRBV22-1-STAD (DFS)

Explore this curve interactively →