TRBV21OR9-2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRBV21OR9-2 mutation is significantly associated with the RNA expression of many other genes, with 440 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRBV21OR9-2-associated genes across cancer lineages are TMEM38B, CINP, and PIAS4. Each is linked with TRBV21OR9-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRBV21OR9-2-to-partner and partner-to-TRBV21OR9-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV21OR9-2→partner) and Y-score (partner→TRBV21OR9-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTMEM38B →+0.817+3.601<.001.00132
UCECCINP →+0.286+3.354.009.00532
UCECPIAS4 →+0.398+3.201.002.00932
SKCMMED18 →+0.486+3.195.002.00932
UCECRRP8 →+0.371+3.467.002.00232
SKCMST7L →+0.575+3.341<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 440 associations by consensus.

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