TRBV21-1

Across TCGA patient cohorts, TRBV21-1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,618 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRBV21-1-associated proteins across cancer lineages are DOCK10, DOK2, and GBP1. Each is linked with TRBV21-1 in more than 7 cancer types. Because this analysis shows association rather than direction, both TRBV21-1-to-partner and partner-to-TRBV21-1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRBV21-1 versus DOCK10 in LSCC, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV21-1→partner) and Y-score (partner→TRBV21-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DOCK10 →	+0.464	+0.532	<.001	<.001	3	8
HNSC	DOK2 →	+0.562	+0.962	<.001	<.001	3	8
BRCA	GBP1 →	+0.655	+0.422	<.001	<.001	3	8
LSCC	IL16 →	+0.619	+0.599	<.001	<.001	3	8
BRCA	WAS →	+0.415	+0.429	<.001	<.001	3	8
LSCC	ARHGEF6_S225 →	+0.669	+0.471	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,618 associations by consensus.

TRBV21-1 vs DOCK10 — LSCC

Explore this scatter interactively →