Across TCGA patient cohorts, TRBV2 mutation is significantly associated with the RNA expression of many other genes, with 189 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRBV2-associated genes across cancer lineages are RNU6-1113P, LINC01858, and RNA5SP430. Each is linked with TRBV2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRBV2-to-partner and partner-to-TRBV2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV2→partner) and Y-score (partner→TRBV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-1113P →	+0.190	+5.339	<.001	.001	3	2
LUAD	LINC01858 →	+0.180	+3.211	.002	.003	3	2
LUSC	RNA5SP430 →	+0.442	+5.882	<.001	.002	3	2
SKCM	KCNH1-IT1 →	+0.719	+2.826	<.001	.001	3	1
SKCM	S100A11P2 →	+0.162	+2.169	.002	.005	3	1
SKCM	SNORD13P3 →	+0.184	+2.178	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 189 associations by consensus.

Exploration

TRBV2 survival (RNA) · tumor vs normal (RNA) · all TRBV2 data types