Across TCGA patient cohorts, TRBV19 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRBV19-associated genes across cancer lineages are INPP4B, S6_pS240_S244, and BRCA2. Each is linked with TRBV19 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRBV19-to-partner and partner-to-TRBV19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV19→partner) and Y-score (partner→TRBV19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.467	-2.986	.012	.037	3	2
UCEC	S6_pS240_S244 →	+0.494	+3.000	.035	.037	3	1
UCEC	BRCA2 →	-0.198	-2.992	.006	.036	2	1
UCEC	Cyclin-B1 →	+0.774	+3.000	.017	.037	1	2
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.827	+3.000	.004	.037	1	1
UCEC	Rictor_pT1135 →	-0.117	-3.000	.047	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

TRBV19 survival (RNA) · tumor vs normal (RNA) · all TRBV19 data types