TRBV11-3

Across TCGA patient cohorts, TRBV11-3 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,743 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRBV11-3-associated proteins across cancer lineages are STK10, EVL, and ANKRD44. Each is linked with TRBV11-3 in more than 6 cancer types. Because this analysis shows association rather than direction, both TRBV11-3-to-partner and partner-to-TRBV11-3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRBV11-3 versus STK10 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV11-3→partner) and Y-score (partner→TRBV11-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	STK10 →	+0.382	+0.432	<.001	<.001	3	7
HNSC	EVL →	+0.487	+0.496	.004	<.001	3	7
LSCC	ANKRD44 →	+0.420	+0.499	<.001	<.001	3	7
OV	LIMD2 →	+0.788	+0.234	<.001	.002	3	7
OV	ARHGAP25 →	+0.845	+0.434	.002	<.001	3	7
LSCC	STK4 →	+0.352	+0.417	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,743 associations by consensus.

TRBV11-3 vs STK10 — LSCC

Explore this scatter interactively →