TRBC2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRBC2 mutation is significantly associated with the RNA expression of many other genes, with 2,701 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRBC2-associated genes across cancer lineages are GPN2, TRAPPC2L, and MIR182. Each is linked with TRBC2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRBC2-to-partner and partner-to-TRBC2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBC2→partner) and Y-score (partner→TRBC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGPN2 →+0.410+3.595<.001.00133
UCECTRAPPC2L →+0.387+3.502.004.00233
HNSCMIR182 →+0.249+3.478.002.00832
HNSCRAB28P3 →+0.102+4.597<.001<.00132
HNSCSNORD127 →+0.637+3.718.001.00632
HNSCRNA5SP417 →+0.272+4.608<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,701 associations by consensus.

Exploration