Across TCGA patient cohorts, TRAV8-6 mutation is significantly associated with the RNA expression of many other genes, with 240 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV8-6-associated genes across cancer lineages are DUX4L17, TEX29, and LINC02262. Each is linked with TRAV8-6 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV8-6-to-partner and partner-to-TRAV8-6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV8-6→partner) and Y-score (partner→TRAV8-6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	DUX4L17 →	+0.009	+4.025	<.001	.007	3	2
SKCM	TEX29 →	+0.492	+2.542	.004	.009	3	2
LUSC	LINC02262 →	+0.161	+3.333	.002	.004	3	2
LUSC	LINC02115 →	+0.277	+3.624	<.001	.008	3	2
SKCM	MIR8078 →	+0.564	+2.498	<.001	.002	3	1
SKCM	MIR7845 →	+0.330	+2.770	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 240 associations by consensus.

Exploration

TRAV8-6 survival (RNA) · tumor vs normal (RNA) · all TRAV8-6 data types