Across TCGA patient cohorts, TRAV41 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAV41-associated genes across cancer lineages are PYDC2, LINC02281, and LINC02330. Each is linked with TRAV41 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV41-to-partner and partner-to-TRAV41 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV41→partner) and Y-score (partner→TRAV41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PYDC2 →	+0.267	+6.382	<.001	.001	3	1
BRCA	LINC02281 →	+0.143	+6.215	<.001	.001	3	1
BRCA	LINC02330 →	+0.145	+5.409	<.001	.005	3	1
UCEC	MIR6859-2 →	+0.781	+3.690	<.001	.009	3	1
UCEC	RNA5SP414 →	+0.972	+3.840	<.001	.007	3	1
UCEC	MIR6515 →	+0.531	+4.750	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

TRAV41 survival (RNA) · tumor vs normal (RNA) · all TRAV41 data types