Across TCGA patient cohorts, TRAV40 mutation is significantly associated with the RNA expression of many other genes, with 68 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAV40-associated genes across cancer lineages are MIR6082, COPS8P1, and HNRNPCL3. Each is linked with TRAV40 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV40-to-partner and partner-to-TRAV40 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV40→partner) and Y-score (partner→TRAV40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6082 →	+0.186	+7.471	<.001	.008	3	1
UCEC	COPS8P1 →	+0.122	+2.842	<.001	.007	3	1
UCEC	HNRNPCL3 →	+0.065	+2.871	<.001	.007	3	1
SKCM	RN7SL210P →	+0.110	+3.947	<.001	.002	3	1
UCEC	CBX3P1 →	+0.388	+4.028	<.001	<.001	3	1
BRCA	NEUROD6 →	+0.044	+5.926	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

Exploration

TRAV40 survival (RNA) · tumor vs normal (RNA) · all TRAV40 data types