Across TCGA patient cohorts, TRAV38-1 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV38-1-associated genes across cancer lineages are FAM230F, MIR8080, and NMBR-AS1. Each is linked with TRAV38-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV38-1-to-partner and partner-to-TRAV38-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV38-1→partner) and Y-score (partner→TRAV38-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAM230F →	+0.416	+5.877	<.001	.001	3	1
UCEC	MIR8080 →	+0.495	+5.335	<.001	.003	3	1
SKCM	NMBR-AS1 →	+0.131	+4.098	<.001	.001	3	1
SKCM	LINC02220 →	+0.321	+3.560	<.001	.002	3	1
SKCM	CSTP2 →	+0.071	+4.021	<.001	.002	3	1
UCEC	MIR3619 →	+0.915	+4.188	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

TRAV38-1 survival (RNA) · tumor vs normal (RNA) · all TRAV38-1 data types