Across TCGA pan-cancer cohorts, TRAV32 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TRAV32’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TRAV32 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRAV32 is over-expressed in tumor.
KIRC and KIRP are the cancer types where TRAV32 tumor–normal differential expression is most reproducible.