Across TCGA patient cohorts, TRAV25 mutation is significantly associated with the RNA expression of many other genes, with 136 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAV25-associated genes across cancer lineages are CYTH1P1, MIR520E, and RPL31P47. Each is linked with TRAV25 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV25-to-partner and partner-to-TRAV25 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV25→partner) and Y-score (partner→TRAV25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CYTH1P1 →	+0.166	+4.184	.003	.004	3	2
LUSC	MIR520E →	+0.406	+7.924	<.001	.008	3	2
UCEC	RPL31P47 →	+0.584	+3.969	<.001	.005	3	2
UCEC	SNHG27 →	+0.252	+4.838	.008	<.001	3	2
SKCM	EEF1E1-BLOC1S5 →	+0.055	+3.351	<.001	.008	3	2
UCEC	SNORD11B →	+1.112	+4.061	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 136 associations by consensus.

Exploration

TRAV25 survival (RNA) · tumor vs normal (RNA) · all TRAV25 data types