TRAV23DV6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRAV23DV6 mutation is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV23DV6-associated genes across cancer lineages are TMEM97P2, RNA5SP485, and TRBV8-1. Each is linked with TRAV23DV6 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV23DV6-to-partner and partner-to-TRAV23DV6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV23DV6→partner) and Y-score (partner→TRAV23DV6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCATMEM97P2 →+0.113+5.378<.001.00632
BLCARNA5SP485 →+0.358+7.640<.001.00932
UCECTRBV8-1 →+0.326+5.109.009.00132
SKCMMIR548H3 →+0.452+4.867<.001.00532
BRCAPOTEB3 →+0.027+4.995<.001.00931
BRCAH3P34 →+0.190+5.841<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

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