Across TCGA patient cohorts, TRAV18 mutation is significantly associated with the RNA expression of many other genes, with 213 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV18-associated genes across cancer lineages are NTAN1, SNORA70D, and BNIP3. Each is linked with TRAV18 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV18-to-partner and partner-to-TRAV18 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV18→partner) and Y-score (partner→TRAV18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NTAN1 →	+0.578	+3.353	<.001	.005	3	2
BLCA	SNORA70D →	+0.423	+5.685	<.001	.003	3	2
SKCM	BNIP3 →	+0.961	+3.328	<.001	.005	3	2
SKCM	RNA5SP328 →	+0.110	+4.049	<.001	.007	3	2
UCEC	MRPL17 →	+0.479	+3.191	.004	.009	3	2
UCEC	STMN1P1 →	+0.563	+3.523	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 213 associations by consensus.

Exploration

TRAV18 survival (RNA) · tumor vs normal (RNA) · all TRAV18 data types