Across TCGA patient cohorts, TRAV12-3 mutation is significantly associated with the RNA expression of many other genes, with 77 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV12-3-associated genes across cancer lineages are RN7SKP86, RNA5SP180, and SNRPGP17. Each is linked with TRAV12-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV12-3-to-partner and partner-to-TRAV12-3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV12-3→partner) and Y-score (partner→TRAV12-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP86 →	+0.581	+3.661	<.001	.009	3	2
LUAD	RNA5SP180 →	+0.587	+5.798	<.001	.003	3	2
UCEC	SNRPGP17 →	+0.428	+3.879	.004	.008	3	2
HNSC	OR6C76 →	+0.074	+5.069	<.001	.008	3	1
HNSC	KRTAP20-4 →	+1.580	+6.008	<.001	.002	3	1
HNSC	RNU6-1181P →	+0.376	+6.008	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 77 associations by consensus.

Exploration

TRAV12-3 survival (RNA) · tumor vs normal (RNA) · all TRAV12-3 data types