TRAPPC6A

Across TCGA patient cohorts, TRAPPC6A mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAPPC6A-associated genes across cancer lineages are CD4+ Tem, CD8+ Tcm, and Memory B-cells. Each is linked with TRAPPC6A in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAPPC6A-to-partner and partner-to-TRAPPC6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tem grouped by TRAPPC6A-low versus TRAPPC6A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC6A→partner) and Y-score (partner→TRAPPC6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CD4+ Tem →	+0.102	+5.624	<.001	.039	3	1
UCEC	CD8+ Tcm →	+0.061	+2.935	<.001	.046	3	1
UCEC	Memory B-cells →	+0.053	+2.973	.005	.035	3	1
UCEC	B-cells →	+0.076	+2.573	<.001	.037	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CD4+ Tem by TRAPPC6A expression — SKCM

Explore this box plot interactively →