TRAPPC3L

Across TCGA patient cohorts, TRAPPC3L mutation is significantly associated with the RNA expression of many other genes, with 364 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAPPC3L-associated genes across cancer lineages are MIR6894, RPL23AP56, and TRDD1. Each is linked with TRAPPC3L in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAPPC3L-to-partner and partner-to-TRAPPC3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6894 grouped by TRAPPC3L-low versus TRAPPC3L-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC3L→partner) and Y-score (partner→TRAPPC3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6894 →	+0.448	+4.506	<.001	.009	3	2
COAD	RPL23AP56 →	+0.093	+4.392	<.001	.006	3	2
BRCA	TRDD1 →	+0.682	+7.473	<.001	.007	3	1
UCEC	NTAN1P1 →	+0.085	+3.615	.007	<.001	3	1
UCEC	MIR7702 →	+0.263	+4.475	<.001	.003	3	1
UCEC	SNORD116-4 →	+0.973	+2.595	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 364 associations by consensus.

MIR6894 by TRAPPC3L expression — BRCA

Explore this box plot interactively →