TRAPPC3L

Across TCGA pan-cancer cohorts, TRAPPC3L RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated TRAPPC3L data layer compared with 1 for mutation status.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher TRAPPC3L RNA is associated with better overall survival. In most high-consensus cancer types, elevated TRAPPC3L expression acts as an unfavorable survival marker, although some lineages such as SKCM and KIRC show a favorable association.

SKCM, KIRC, and COAD are the cancer types where TRAPPC3L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.406	0.269	<.001	110	view →
KIRC	DFS	Tertile	All	0.724	0.552	<.001	75	view →
COAD	OS	Quartile	II,III,IV	0.946	0.801	.001	66	view →
BLCA	OS	Tertile	IV	0.182	0.529	.002	46	view →
LUAD	OS	Median	II,III,IV	0.699	0.472	.001	33	view →
UVM	OS	Median	III,IV	0.403	0.863	.005	30	view →
ESCA	DFS	Quartile	III,IV	0.671	0.245	.002	22	view →
KIRP	DFS	Median	III,IV	0.144	0.716	.011	20	view →
HNSC	DFS	Tertile	III,IV	0.652	0.505	.006	20	view →
CHOL	DFS	Tertile	All	0.837	0.147	<.001	17	view →
LUSC	OS	Tertile	All	0.829	0.714	.008	14	view →
LGG	OS	Quartile	All	0.715	0.885	.007	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

TRAPPC3L–SKCM (OS)

Open the SKCM breakdown →