TRAPPC2L

Across TCGA patient cohorts, TRAPPC2L RNA expression is significantly associated with the mutation status of many other genes, with 11,414 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAPPC2L-associated genes across cancer lineages are ATM, ZNF536, and LAMA1. Each is linked with TRAPPC2L in more than 3 cancer types. Because this analysis shows association rather than direction, both TRAPPC2L-to-partner and partner-to-TRAPPC2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by TRAPPC2L-low versus TRAPPC2L-high in LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC2L→partner) and Y-score (partner→TRAPPC2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	ATM →	+3.632	+0.289	.001	.009	3	4
UCEC	ZNF536 →	+1.136	+0.314	<.001	<.001	3	4
UCEC	LAMA1 →	+1.981	+0.421	<.001	<.001	3	4
UCEC	KDM5B →	+1.503	+0.309	<.001	<.001	3	4
UCEC	KIAA1109 →	+1.686	+0.368	<.001	<.001	3	4
UCEC	ADAMTS18 →	+2.075	+0.384	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,414 associations by consensus.

ATM by TRAPPC2L expression — LUSC

Explore this box plot interactively →