TRAPPC2L

Across TCGA cell cohorts, TRAPPC2L mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRAPPC2L-associated genes across cancer lineages are TMCO5A, BTNL2, and PRAMEF20. Each is linked with TRAPPC2L in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAPPC2L-to-partner and partner-to-TRAPPC2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMCO5A grouped by TRAPPC2L-low versus TRAPPC2L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC2L→partner) and Y-score (partner→TRAPPC2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TMCO5A →	+0.019	+4.415	<.001	.007	3	1
LARGE_INTESTINE	BTNL2 →	+0.081	+4.415	<.001	.007	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.015	+5.022	<.001	.002	3	1
LARGE_INTESTINE	ACSM6 →	+0.032	+4.169	<.001	.007	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

TMCO5A by TRAPPC2L expression — LARGE_INTESTINE

Explore this box plot interactively →