TRAPPC13

Across TCGA patient cohorts, TRAPPC13 mutation is significantly associated with the RNA expression of many other genes, with 607 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAPPC13-associated genes across cancer lineages are RNA5SP407, MTND6P17, and FDPSP6. Each is linked with TRAPPC13 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAPPC13-to-partner and partner-to-TRAPPC13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP407 grouped by TRAPPC13-low versus TRAPPC13-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC13→partner) and Y-score (partner→TRAPPC13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP407 →	+0.397	+7.924	<.001	.008	3	2
LUSC	MTND6P17 →	+0.103	+7.924	<.001	.008	3	2
SKCM	FDPSP6 →	+0.093	+4.979	<.001	.009	3	2
UCEC	NUDT19P5 →	+0.155	+1.737	<.001	.007	3	2
SKCM	LLPHP1 →	+0.106	+4.979	.002	.009	3	2
BLCA	LINC02871 →	+0.104	+5.788	.008	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 607 associations by consensus.

RNA5SP407 by TRAPPC13 expression — LUSC

Explore this box plot interactively →