TRAPPC13

Across TCGA pan-cancer cohorts, TRAPPC13 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of TRAPPC13’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where TRAPPC13 RNA is repressed in tumor relative to normal tissue. In most cancer types TRAPPC13 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

THCA, LIHC, and LUSC are the cancer types where TRAPPC13 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRAPPC13 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	IV	−0.569	<.001	10	view →
LIHC	Female	II,III,IV	+0.811	<.001	9	view →
LUSC	Male	All	−0.306	<.001	6	view →
KIRC	Male	All	−0.306	<.001	6	view →
BRCA	All	II,III,IV	+0.293	<.001	6	view →
CHOL	All	All	+1.285	<.001	4	view →
KICH	All	All	−0.585	.001	4	view →
HNSC	Female	III,IV	+0.417	.039	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

TRAPPC13–THCA

Open the THCA breakdown →