TRAP1

Across TCGA cell cohorts, TRAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,870 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TRAP1-associated GO terms across cancer lineages are rRNA modification, rRNA pseudouridine synthesis, and Ribosome assembly. Each is linked with TRAP1 in more than 18 cancer types. Because this analysis shows association rather than direction, both TRAP1-to-partner and partner-to-TRAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA modification grouped by TRAP1-low versus TRAP1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAP1→partner) and Y-score (partner→TRAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	rRNA modification →	+0.121	+1.023	<.001	<.001	3	19
BLOOD_Myeloma	rRNA pseudouridine synthesis →	+0.138	+1.166	<.001	<.001	3	18
LARGE_INTESTINE	Ribosome assembly →	+0.092	+1.093	<.001	<.001	3	17
LUNG_SCLC	Enzyme-directed rRNA pseudouridine synthesis →	+0.185	+1.378	<.001	<.001	3	17
LUNG_SCLC	Mitochondrial ribosome assembly →	+0.116	+1.233	<.001	<.001	1	19
URINARY_TRACT	'de novo' IMP biosynthetic process →	+0.202	+1.291	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,870 associations by consensus.

rRNA modification by TRAP1 expression — LIVER

Explore this box plot interactively →