TRAM1

Across TCGA patient cohorts, TRAM1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,305 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRAM1-associated genes across cancer lineages are STKLD1, HDAC5, and RPAIN. Each is linked with TRAM1 in more than 5 cancer types. Because this analysis shows association rather than direction, both TRAM1-to-partner and partner-to-TRAM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRAM1 versus STKLD1 in HNSC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAM1→partner) and Y-score (partner→TRAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	STKLD1 →	-0.486	-0.351	<.001	.002	3	6
UCEC	HDAC5 →	-0.407	-0.302	.006	.006	3	5
HNSC	RPAIN →	-0.644	-0.352	<.001	.001	3	5
LSCC	WDR74 →	-0.466	-0.297	<.001	.003	3	5
HNSC	GARNL3 →	-0.692	-0.375	<.001	.001	3	5
HNSC	BPHL →	-0.536	-0.332	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,305 associations by consensus.

TRAM1 vs STKLD1 — HNSC

Explore this scatter interactively →