TRAK2

Across TCGA patient cohorts, TRAK2 mutation is significantly associated with the RNA expression of many other genes, with 2,544 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAK2-associated genes across cancer lineages are RNA5SP432, MIR5585, and TEX13A. Each is linked with TRAK2 in more than 3 cancer types. Because this analysis shows association rather than direction, both TRAK2-to-partner and partner-to-TRAK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP432 grouped by TRAK2-low versus TRAK2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAK2→partner) and Y-score (partner→TRAK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP432 →	+0.419	+4.303	<.001	.009	3	4
LUAD	MIR5585 →	+0.929	+4.171	<.001	.004	3	3
BRCA	TEX13A →	+0.029	+5.601	.003	<.001	3	2
CESC	LINC02559 →	+1.025	+5.342	<.001	.002	3	2
CESC	RNA5SP386 →	+0.375	+4.320	.002	.007	3	2
LUAD	LGALS16 →	+0.463	+4.612	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,544 associations by consensus.

RNA5SP432 by TRAK2 expression — LUAD

Explore this box plot interactively →