TRAK2

Across TCGA cell cohorts, TRAK2 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRAK2-associated genes across cancer lineages are OPALIN, TAAR6, and KCNK16. Each is linked with TRAK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAK2-to-partner and partner-to-TRAK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPALIN grouped by TRAK2-low versus TRAK2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAK2→partner) and Y-score (partner→TRAK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OPALIN →	+0.746	+3.777	<.001	.002	3	2
BLOOD_Myeloma	TAAR6 →	+0.043	+4.807	<.001	.006	3	1
BLOOD_Myeloma	KCNK16 →	+0.030	+4.807	<.001	.006	3	1
OVARY	FXYD4 →	+0.974	+3.925	<.001	.001	3	1
OVARY	TEX43 →	+0.086	+3.339	<.001	.004	3	1
OVARY	CSH2 →	+0.781	+3.381	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

OPALIN by TRAK2 expression — BLOOD_Leukemia

Explore this box plot interactively →