TRAK1

Across TCGA cell cohorts, TRAK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,695 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRAK1-associated GO terms across cancer lineages are Golgi to endosome transport, Mitochondrion distribution, and Regulation of translation at postsynapse, modulating synaptic transmission. Each is linked with TRAK1 in more than 13 cancer types. Because this analysis shows association rather than direction, both TRAK1-to-partner and partner-to-TRAK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi to endosome transport grouped by TRAK1-low versus TRAK1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAK1→partner) and Y-score (partner→TRAK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Golgi to endosome transport →	+0.117	+1.098	<.001	<.001	3	14
SKIN	Mitochondrion distribution →	+0.093	+0.746	<.001	<.001	3	12
BLOOD_Lymphoma	Regulation of translation at postsynapse, modulating synaptic transmission →	+0.087	+0.789	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.071	+0.992	<.001	<.001	3	11
KIDNEY	Negative regulation of chromosome condensation →	+0.129	+1.027	<.001	<.001	3	10
KIDNEY	Positive regulation of T-helper 17 cell lineage commitment →	+0.183	+0.774	<.001	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,695 associations by consensus.

Golgi to endosome transport by TRAK1 expression — BONE

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