TRAJ55

Across TCGA pan-cancer cohorts, TRAJ55 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated TRAJ55 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher TRAJ55 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TRAJ55 expression acts as an unfavorable survival marker, although some lineages such as SKCM and THYM show a favorable association.

THCA, KIRC, and CHOL are the cancer types where TRAJ55 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.262	0.951	<.001	108	view →
KIRC	DFS	Tertile	IV	0.180	0.635	<.001	36	view →
CHOL	OS	Tertile	All	0.089	0.727	.001	27	view →
KIRP	OS	Tertile	All	0.117	0.707	<.001	27	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	24	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
LUAD	OS	Tertile	IV	0.153	0.714	.012	18	view →
SKCM	OS	Tertile	All	0.619	0.308	.022	9	view →
LGG	DFS	Tertile	All	0.356	0.731	.034	9	view →
DLBC	DFS	Tertile	II,III,IV	0.487	0.793	.044	4	view →
COAD	OS	Tertile	All	0.701	0.871	.042	3	view →
THYM	OS	Median	All	1.000	0.948	.029	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

TRAJ55–THCA (OS)

Open the THCA breakdown →