Across TCGA pan-cancer cohorts, TRAJ52 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TRAJ52’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where TRAJ52 RNA is repressed in tumor relative to normal tissue. In most cancer types TRAJ52 is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.

PAAD and BRCA are the cancer types where TRAJ52 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRAJ52 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PAAD	All	All	−0.777	.028	4	view →
BRCA	Female	All	+0.124	.035	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TRAJ52 RNA expression & survival · all TRAJ52 data types