Across TCGA pan-cancer cohorts, TRAJ48 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TRAJ48’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TRAJ48 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRAJ48 is over-expressed in tumor.
KIRC and BRCA are the cancer types where TRAJ48 tumor–normal differential expression is most reproducible.