Across TCGA pan-cancer cohorts, TRAJ28 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated TRAJ28 data layer.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher TRAJ28 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRAJ28 expression acts as an unfavorable survival marker, although some lineages such as HNSC and KIRC show a favorable association.
LUSC, HNSC, and DLBC are the cancer types where TRAJ28 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.