Across TCGA pan-cancer cohorts, TRAJ28 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of TRAJ28’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where TRAJ28 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRAJ28 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

STAD, THCA, and KICH are the cancer types where TRAJ28 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRAJ28 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	+0.407	.017	2	view →
THCA	Female	All	−0.158	.049	1	view →
KICH	All	All	+0.123	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: TRAJ28 RNA expression & survival · all TRAJ28 data types