Across TCGA patient cohorts, TRAJ23 mutation is significantly associated with the RNA expression of many other genes, with 75 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAJ23-associated genes across cancer lineages are LINC02210-CRHR1, RAC1P7, and SRIP1. Each is linked with TRAJ23 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAJ23-to-partner and partner-to-TRAJ23 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAJ23→partner) and Y-score (partner→TRAJ23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02210-CRHR1 →	+0.107	+3.759	.004	.005	3	2
SKCM	RAC1P7 →	+0.141	+5.624	<.001	.002	3	1
SKCM	SRIP1 →	+0.140	+5.080	<.001	.004	3	1
UCEC	AFM →	+0.210	+3.986	.001	.003	3	1
UCEC	IGHV3OR16-6 →	+0.969	+3.719	<.001	.006	3	1
UCEC	IGHV3OR16-13 →	+1.027	+3.633	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 75 associations by consensus.

Exploration

TRAJ23 survival (RNA) · tumor vs normal (RNA) · all TRAJ23 data types