Across TCGA patient cohorts, TRAJ23 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAJ23-associated genes across cancer lineages are CD8+ T-cells, CD8+ Tcm, and Macrophages. Each is linked with TRAJ23 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAJ23-to-partner and partner-to-TRAJ23 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAJ23→partner) and Y-score (partner→TRAJ23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ T-cells →	+0.024	+3.845	.005	.004	3	1
UCEC	CD8+ Tcm →	+0.068	+3.935	<.001	.003	3	1
UCEC	Macrophages →	+0.030	+3.809	.003	.005	3	1
UCEC	Macrophages M1 →	+0.038	+3.065	<.001	.029	3	1
UCEC	CD4+ memory T-cells →	+0.043	+2.617	<.001	.034	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

TRAJ23 survival (RNA) · tumor vs normal (RNA) · all TRAJ23 data types