Across TCGA patient cohorts, TRAJ12 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAJ12-associated genes across cancer lineages are RN7SL601P, UBE2V1P10, and MIR2053. Each is linked with TRAJ12 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAJ12-to-partner and partner-to-TRAJ12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAJ12→partner) and Y-score (partner→TRAJ12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL601P →	+0.163	+7.816	<.001	.008	3	1
UCEC	UBE2V1P10 →	+0.154	+8.066	<.001	.007	3	1
UCEC	MIR2053 →	+0.637	+8.066	<.001	.007	3	1
SKCM	RNU6-624P →	+0.383	+7.816	<.001	.008	3	1
SKCM	DEFB109C →	+0.179	+7.816	<.001	.008	3	1
SKCM	MIR9-1 →	+0.383	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

TRAJ12 survival (RNA) · tumor vs normal (RNA) · all TRAJ12 data types