Q-omics provides the consensus-scored DEFB109C profile across patient tissues and cancer cell-line models. DEFB109C expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in STAD. Additionally, DEFB109C RNA expression shows 4,826 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight STAD, and GBM as cancer lineages where DEFB109C shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes DEFB109C survival associations across molecular data types. DEFB109C RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

DEFB109C data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	5	THYM (36)	view →

This table ranks reproducible DEFB109C RNA expression–survival associations across cancer types. High DEFB109C expression shows unfavorable associations in STAD, TGCT, SARC, THYM and OV. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .004). Together, the overview and detailed table identify STAD as the clearest survival context for DEFB109C RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Tertile	All	0.384	0.677	.004	36	view →
TGCT	OS	Tertile	All	0.069	0.968	<.001	36	view →
SARC	OS	Tertile	All	0.133	0.860	<.001	36	view →
THYM	DFS	Tertile	II,III,IV	0.145	0.873	<.001	36	view →
OV	DFS	Tertile	IV	0.194	0.478	.016	18	view →

Pink = unfavorable, green = favorable. all 5 lineages →

DEFB109C-STAD (OS)

Kaplan–Meier survival curve for DEFB109C RNA expression in STAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with DEFB109C in patient tissues and cancer cell lines. In patient samples, DEFB109C shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Protein (mass-spec)	4,826	GBM (2683)	view →
RNA	2,567	LUAD (1673)	view →