TRAF3IP3

Across TCGA patient cohorts, TRAF3IP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,997 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRAF3IP3-associated proteins across cancer lineages are ARHGEF6, ARHGEF6_S684, and PSMB10. Each is linked with TRAF3IP3 in more than 9 cancer types. Because this analysis shows association rather than direction, both TRAF3IP3-to-partner and partner-to-TRAF3IP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRAF3IP3 versus ARHGEF6 in LSCC, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAF3IP3→partner) and Y-score (partner→TRAF3IP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGEF6 →	+0.478	+0.817	<.001	<.001	3	10
OV	ARHGEF6_S684 →	+0.813	+0.623	.001	.008	3	10
LSCC	PSMB10 →	+0.511	+0.766	<.001	<.001	3	10
COAD	PTPN7 →	+0.629	+0.869	<.001	<.001	3	10
GBM	PTPRC →	+0.824	+0.738	<.001	<.001	3	10
BRCA	RAC2 →	+0.870	+0.883	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,997 associations by consensus.

TRAF3IP3 vs ARHGEF6 — LSCC

Explore this scatter interactively →