TRAF3IP3

Across TCGA patient cohorts, TRAF3IP3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,474 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRAF3IP3-associated genes across cancer lineages are NCF4, BIN2, and CD48. Each is linked with TRAF3IP3 in more than 9 cancer types. Because this analysis shows association rather than direction, both TRAF3IP3-to-partner and partner-to-TRAF3IP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRAF3IP3 versus NCF4 in UCEC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAF3IP3→partner) and Y-score (partner→TRAF3IP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCF4 →	+1.150	+0.706	<.001	<.001	3	10
HNSC	BIN2 →	+1.174	+0.631	<.001	<.001	3	10
HNSC	CD48 →	+1.226	+0.541	<.001	<.001	3	10
LSCC	LAX1 →	+1.503	+0.736	<.001	<.001	3	10
LSCC	FCRL2 →	+1.233	+0.678	<.001	<.001	3	10
HNSC	GPR65 →	+0.898	+0.579	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,474 associations by consensus.

TRAF3IP3 vs NCF4 — UCEC

Explore this scatter interactively →