TRAF3IP3

Across TCGA cell cohorts, TRAF3IP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,603 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRAF3IP3-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with TRAF3IP3 in more than 10 cancer types. Because this analysis shows association rather than direction, both TRAF3IP3-to-partner and partner-to-TRAF3IP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by TRAF3IP3-low versus TRAF3IP3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAF3IP3→partner) and Y-score (partner→TRAF3IP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.150	+0.491	<.001	<.001	3	11
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.146	+0.491	<.001	<.001	3	10
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.121	+0.441	<.001	<.001	3	10
OESOPHAGUS	Regulation of myoblast fusion →	+0.130	+0.477	<.001	<.001	3	9
OESOPHAGUS	Spliceosomal complex assembly →	+0.155	+0.630	<.001	<.001	3	9
LARGE_INTESTINE	Mitochondrial electron transport, cytochrome c to oxygen →	+0.072	+0.248	<.001	.001	1	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,603 associations by consensus.

Negative regulation of myoblast fusion by TRAF3IP3 expression — OESOPHAGUS

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