TRAF3IP2-AS1

Across TCGA pan-cancer cohorts, TRAF3IP2-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of TRAF3IP2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where TRAF3IP2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types TRAF3IP2-AS1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, LIHC, and THCA are the cancer types where TRAF3IP2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRAF3IP2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−1.309	<.001	9	view →
LIHC	Female	II,III,IV	+0.360	<.001	9	view →
THCA	Male	III,IV	−0.615	<.001	8	view →
LUSC	All	III,IV	−0.735	.001	7	view →
BRCA	All	III,IV	−0.628	<.001	6	view →
CHOL	All	All	+0.786	<.001	5	view →
UCEC	All	All	−0.678	<.001	4	view →
LUAD	Female	III,IV	−0.630	<.001	4	view →
BLCA	Male	IV	−0.607	.019	2	view →
PRAD	All	All	−0.289	<.001	2	view →
HNSC	All	III,IV	+0.183	.028	2	view →
KIRC	Male	II,III,IV	−0.207	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

TRAF3IP2-AS1–KICH

Open the KICH breakdown →