TRAF2

Across TCGA cell cohorts, TRAF2 protein abundance is significantly associated with the go_rna of many other GO terms, with 1,233 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible TRAF2-associated GO terms across cancer lineages are Late endosome to Golgi transport, Positive regulation of secondary metabolite biosynthetic process, and Telomere assembly. Each is linked with TRAF2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRAF2-to-partner and partner-to-TRAF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Late endosome to Golgi transport grouped by TRAF2-low versus TRAF2-high in BREAST.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAF2→partner) and Y-score (partner→TRAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Late endosome to Golgi transport →	+0.158	+1.226	<.001	.002	3	3
LUNG_NSCLC_LUAD	Positive regulation of secondary metabolite biosynthetic process →	+0.164	+1.650	<.001	.005	3	2
LUNG_NSCLC_LUAD	Telomere assembly →	-0.210	-1.477	.004	.005	2	3
LUNG_NSCLC_LUAD	Lipid translocation →	+0.089	+1.873	.007	.001	3	2
LUNG_NSCLC_LUAD	Corticosteroid hormone secretion →	+0.185	+1.477	.004	.005	3	2
LUNG_NSCLC_LUAD	Positive regulation of melanin biosynthetic process →	+0.164	+1.650	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,233 associations by consensus.

Late endosome to Golgi transport by TRAF2 expression — BREAST

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