TRABD

Across TCGA cell cohorts, TRABD mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRABD-associated genes across cancer lineages are OR2B2, KCNK17, and NAT8. Each is linked with TRABD in more than 1 cancer types. Because this analysis shows association rather than direction, both TRABD-to-partner and partner-to-TRABD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2B2 grouped by TRABD-low versus TRABD-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRABD→partner) and Y-score (partner→TRABD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR2B2 →	+0.019	+4.684	.007	.002	3	2
LARGE_INTESTINE	KCNK17 →	+0.061	+3.906	<.001	.002	3	1
LARGE_INTESTINE	NAT8 →	+0.567	+3.443	.003	.009	3	1
LARGE_INTESTINE	OR10W1 →	+0.014	+3.562	<.001	.002	3	1
LARGE_INTESTINE	TAFA1 →	+0.234	+3.103	.002	.004	3	1
LARGE_INTESTINE	C14orf180 →	+0.155	+3.477	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OR2B2 by TRABD expression — SKIN

Explore this box plot interactively →